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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1
All Species:
46.36
Human Site:
S218
Identified Species:
72.86
UniProt:
P48729
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48729
NP_001020276.1
337
38915
S218
L
M
Y
F
N
R
T
S
L
P
W
Q
G
L
K
Chimpanzee
Pan troglodytes
XP_001163892
341
39357
S222
L
M
Y
F
N
R
T
S
L
P
W
Q
G
L
K
Rhesus Macaque
Macaca mulatta
XP_001106705
339
39093
S220
L
M
Y
F
N
R
T
S
L
P
W
Q
G
L
K
Dog
Lupus familis
XP_867638
336
38749
S218
L
M
Y
F
N
R
T
S
L
P
W
Q
G
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
S210
L
M
Y
F
N
L
G
S
L
P
W
Q
G
L
K
Rat
Rattus norvegicus
P97633
325
37477
D203
I
E
Q
S
R
R
D
D
M
E
S
L
G
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
S218
L
M
Y
F
N
R
T
S
L
P
W
Q
G
L
K
Frog
Xenopus laevis
Q5BP74
415
47421
S210
L
M
Y
F
N
L
G
S
L
P
W
Q
G
L
K
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
S210
L
M
Y
F
N
L
G
S
L
P
W
Q
G
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
M214
M
E
S
L
G
Y
V
M
M
Y
F
N
R
G
V
Honey Bee
Apis mellifera
XP_393612
350
40282
S222
L
M
Y
F
N
R
G
S
L
P
W
Q
G
L
K
Nematode Worm
Caenorhab. elegans
P42168
341
39018
T217
L
M
Y
F
N
R
G
T
L
P
W
Q
G
L
K
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
D217
I
E
Q
S
R
R
D
D
L
E
S
L
G
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
S210
L
M
Y
F
L
K
G
S
L
P
W
Q
G
L
K
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
S210
L
I
Y
F
C
K
G
S
L
P
W
Q
G
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.6
99.6
N.A.
57.2
96.1
N.A.
N.A.
99.6
57.5
59.5
N.A.
74.1
80.8
81.2
78.7
Protein Similarity:
100
98.8
98.2
99.6
N.A.
67.7
96.1
N.A.
N.A.
100
67.9
70.2
N.A.
82.7
86.8
86.8
87.3
P-Site Identity:
100
100
100
100
N.A.
86.6
13.3
N.A.
N.A.
100
86.6
86.6
N.A.
0
93.3
86.6
20
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
N.A.
100
86.6
86.6
N.A.
20
93.3
93.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.2
41.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.1
54.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
14
14
0
0
0
0
0
0
0
% D
% Glu:
0
20
0
0
0
0
0
0
0
14
0
0
0
0
0
% E
% Phe:
0
0
0
80
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
47
0
0
0
0
0
94
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
80
% K
% Leu:
80
0
0
7
7
20
0
0
87
0
0
14
0
80
0
% L
% Met:
7
74
0
0
0
0
0
7
14
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
67
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% P
% Gln:
0
0
14
0
0
0
0
0
0
0
0
80
0
0
0
% Q
% Arg:
0
0
0
0
14
60
0
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
7
14
0
0
0
74
0
0
14
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
34
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% W
% Tyr:
0
0
80
0
0
7
0
0
0
7
0
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _